Because rue tea can cause serious toxicity, there is no medically established safe daily amount, so most experts advise avoiding rue tea entirely.

For facial skin, salicylic acid between 0.5% and 2% suits most people when matched to skin type and used in a simple, consistent routine.

Most doctors consider topical salicylic acid products up to 2% safe in pregnancy when used on small areas for short periods.

Most healthy adults can use about 1–2 tablespoons of safflower oil per day as part of total fat intake, unless told otherwise by a doctor.

Typical SAM-e doses range from 200–1600 mg per day; start low and ask your doctor first, especially if you take other medicines.

Most adults use oral SAM-e in doses from 400 to 1600 mg per day, based on product labels, medical advice, and how their body reacts.

Most people with acne start with 0.5–2% salicylic acid once daily, then adjust based on skin tolerance and product directions.

For most adults, mix rosemary oil at about a 2% dilution, or 2 drops of rosemary per teaspoon (5 ml) of carrier oil for scalp and skin use.