Eating under about 1,200 kcal for most adults is too low long term; set your floor from resting needs, size, sex, and activity.

For insulin, “too much” means dosing that drives blood glucose below 70 mg/dL or causes repeated lows.

Too much methylene blue begins near 7 mg/kg; standard medical dosing stays at 1–2 mg/kg with strict drug-interaction checks.

For toddlers, doses above 1 mg can exceed common starting guidance, so always use the lowest effective amount under pediatric advice.

For delta-8 THC, many adults feel bad effects above 30–40 mg; start with 5–10 mg and wait two hours before any more.

For most patients, doses above 70 mg of Vyvanse a day exceed labeled limits and raise safety risks.

Prednisone daily limits vary by condition; most adult short courses use 5–60 mg, and doses above 60 mg in a day need specialist direction.

Dose tolerance varies; many guidelines flag higher risk above 50 MME/day and discourage exceeding 90 MME/day for chronic pain.

Weekly ibuprofen use should stay within 1,200 mg per day and not extend beyond 10 days without medical guidance.