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At Walgreens without insurance, Zepbound runs about $1,000–$1,300 for a 28-day pen pack, while LillyDirect vials can be $349–$499.

With Anthem plans, Zepbound often runs $25–$499 with coverage/savings; without coverage expect ~$995–$1,300 per month, plan rules apply.

With a Cigna plan, Zepbound costs can range from $25 with savings to a specialty-tier copay or coinsurance after deductibles.

Monthly costs with Aetna range from a plan copay when covered to $349–$1,086 self-pay when excluded, depending on dose and deductible.

Zepbound with insurance often runs $25–$200 per month after savings; without coverage, cash prices run $349–$1,300 by dose and program.

Zepbound self-pay runs $349–$1,086 for 28 days, depending on vial or pen, dose, and where you buy.

Zepbound cash prices run about $995–$1,300 for pens, or $349–$499 for LillyDirect vials, depending on dose and program.

Zepbound 15 mg without insurance runs about $1,000–$1,300 at retail, or $499/month through LillyDirect vials for eligible self-pay users.

Without insurance, the 10 mg strength typically runs about $499 via LillyDirect vials or around $1,000 at retail with coupons.

Through LillyDirect self-pay, a Zepbound 5 mg vial runs $499 for a 28-day supply; most retail pharmacies charge about $1,000–$1,300 per month.